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USA › Road trip gas calculator › Orlando to Key West

Orlando to Key West: gas cost

About 410 miles one way. Fuel cost at this week’s average regular price in Florida: $3.791 per gallon (EIA, week of Nov 2, 2026).

Fuel cost by vehicle

VehicleMPGGallonsOne wayRound trip
Compact car3511.7$44.41$88.82
Midsize sedan3013.7$51.81$103.62
SUV / crossover2417.1$64.76$129.53
Pickup truck1822.8$86.35$172.70

💡 Gas gets pricier toward the Keys – fill up on the mainland before US-1.

Calculate with your own numbers

Popular road trips

RouteMilesGas cost, 30 MPG
Los Angeles → Las Vegas270$51.68
San Francisco → Los Angeles382$73.19
New York City → Washington, D.C.225$30.86
Boston → New York City215$29.58
Chicago → Detroit283$44.39
Dallas → Houston239$28.50
Houston → Austin165$19.94
Miami → Orlando235$30.33
Seattle → Portland174$30.64
Denver → Salt Lake City520$69.61
Los Angeles → San Diego120$22.97
New York City → Boston215$29.48
Chicago → St. Louis297$46.59
Atlanta → Orlando440$54.19
Phoenix → Los Angeles372$59.16
Cleveland → Columbus143$19.53
New York City → Miami1,280$167.94
Los Angeles → New York City2,790$386.23
Chicago → New York City790$108.02
San Francisco → Seattle808$142.64
Dallas → Austin195$23.26
Dallas → San Antonio275$32.80
Houston → New Orleans350$42.42
Houston → San Antonio200$24.17
Austin → San Antonio80$9.54
Dallas → Oklahoma City205$24.45
Atlanta → Nashville250$30.79
Atlanta → Miami660$81.29
Atlanta → Charlotte245$30.18
Nashville → Memphis210$28.71
Chicago → Minneapolis410$64.32
Chicago → Indianapolis185$29.02
Chicago → Milwaukee92$14.43
Detroit → Cleveland170$23.24
New York City → Philadelphia95$13.03
Philadelphia → Washington, D.C.140$19.75
Washington, D.C. → Orlando855$112.18
New York City → Buffalo375$52.71
New York City → Pittsburgh370$52.01
Boston → Portland, Maine110$15.13
Orlando → Tampa85$10.74
Miami → Key West160$20.65
Jacksonville → Miami345$43.60
Seattle → Spokane280$49.31
Portland → San Francisco635$100.99
Los Angeles → Sacramento385$73.77
San Diego → Las Vegas330$63.23
San Diego → Phoenix355$68.02
San Francisco → Las Vegas565$108.25
Phoenix → Las Vegas300$47.71
Las Vegas → Grand Canyon South Rim280$44.53
Salt Lake City → Las Vegas420$58.98
Denver → Las Vegas750$100.40
Denver → Albuquerque450$60.24
Denver → Chicago1,000$135.60
Kansas City → St. Louis250$34.18
Kansas City → Denver600$82.04
Pittsburgh → Philadelphia305$43.03
Columbus → Chicago355$48.40
Cincinnati → Nashville275$37.49
Phoenix → Tucson115$18.29

FAQ

How much does it cost to drive from Orlando to Key West?

At about 410 miles and this week’s average of $3.791 per gallon (Florida), a car averaging 30 MPG uses about 13.7 gallons – roughly $51.81 one way or $103.62 round trip.

How many gallons of gas from Orlando to Key West?

About 11.7 gallons for a 35 MPG car, 17.1 for a 24 MPG SUV and 22.8 for an 18 MPG pickup.

Gas prices by state this week → · Gas price history → · More calculators →

Distances are approximate driving distances. Gas prices: U.S. Energy Information Administration weekly averages for regular gasoline; actual prices along the route vary.